In this small sequel Deus Ex, JC and Paul Denton return to once again to work along side the secretive influence of the Illuminati. It resumes from the Illuminati ending with Morgan Everett in the original ending of Deus Ex. In the process of worldwide vaccination, the Gray death is still a formidable threat to the poor. With wild prices being charged for ridiculous amounts of Ambrosia, the economy is ripping itself in two. Quite clearly being rich is only way to live. Suspicious ripples have been resonating through the diversified Illuminati group, Allied partnerships are questioned. Greed is at its highest, countries willing to go to war over the cure for their civilisation. Whoever controls Ambrosia controls the world.